Salmonella Meningitis in a Two Months Infant from Odisha, India: A Rare Case Report
Keywords:
Salmonella, Cotrimaxozole, Fluroquinoles, Aminoglycosides, Chloramphenicol, S. typhiAbstract
Salmonella meningitis is a disease with high mortality in infants though incidence is rare. This article reports a case of Salmonella meningitis in a two months male infant, who presented with high fever, convulsion and difficulty in breathing. Salmonella typhi was isolated from cerebrospinal fluid (CSF), that showed resistance to Cephalosporins, Fluroquinoles, Macrolides and Aminoglycosides but susceptiblity to Chloramphenicol and Cotrimaxozole. This case was admitted on fourth day of onset of illness and treated with parenteral Vancomycin and Ceftriaxone to cover both gram positive and negative bacterial agents of bacterial meningitis in a young infant, but succumbed to death on ninth day of illness. This indicated importance of S. typhi as a possible bacterial etiology and a great concern on resistance to the normally chosen antibiotics. An early suspicion can be suggested to reduce the risk of mortality. Environmental hygiene and household cleanliness practices also warrants attention, which were identified as possible risks for enteric infection in spite the baby was absolutely breast fed.
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References
American Academy of Pediatrics. Committee on Infectious diseases. Salmonella infections. In: Peter G, editor. Report of the committee on infectious diseases.25th ed. Elk Grove Village, IL: American Academy of Pediatrics; 2000 p. 503.
Duggal S, Rongpharpi S R, Kumar A, Gur R. Salmonella Typhi Meningitis in A Two Year Old Child: A Case Report. National J of Laboratory Medicine, 2015; 4(4): 59-61
Elizabeth H P, Louvois J D, Workman M R. Antibiotics for Salmonella meningitis in children. Antimicob Chemother 2000; 46: 653-655.
Hung-Ming Wu1, Wan-Yu Huang, Meng-Luen Lee, Albert D Yang, Ko-Ping Chaou, Lin-Yu Hsieh. Clinical features, acute complications and outcome of Salmonella meningitis in children under one year of age in Taiwan. BMC Infectious Diseases 2011; 11:30.
Kumar R, Gupta BK, Khurana S. Incidence of Salmonella meningitis in Ludhiana (Punjab). Indian Journal of Pathology & Microbiology 1993; 36(1):1-4.
Lecour H, Seara A, Cordeiro J, Miranda M. Treatment of childhood bacterial meningitis. Infect 1989; 17:343-346.
Molyneux EM, Walsh AL, Malenga G, Rogerson S, Molyneux ME. Salmonella meningitis in children in Blantyre, Malawi, 1996-1999. Ann.Trop. Paediatr. 2000; 20(1):41-4.
Molyneux E M, Mankhambo L A, Phiri A , Graham S M, Forsyth H, Walsh A L, Wilson L K, Molyneux M E. The outcome of non thyphoidal Salmonella meningitis in Malwian children 1997-2006. Ann Trop Pediatr 2009; 29(1): 13-22.
Molyneux E M, Phiri A, Walsh A, Molyneux M E. Acute bacterial meningitis in children admitted to the Queen Elizabeth Central Hospital, Blantre, Malwi in 1996-97. Trop Med & Int Health 1998; 3(8): 610-618.
Nwadike, V. U., Fowotade, A., Tuta, K. E., & Olusanya, O. O. A rare case of salmonella typhi meningitis in an eleven month old infant: a case report. Annals of Ibadan postgraduate medicine 2012; 10(1): 38–39.
Ofori A O, Scheld W M. Treatment of Salmonella meningitis: two case reports and review of the literature. Int J Infect Dis 2003; 7: 53-60.
Preblub S R, Gill C J, Campos J M. Bactericidal activities of Chloramphicol and eleven other antibiotics against Salmonella spp. Antimicrob Agents Chemother 1984; 25(3): 327-330
Price E H, De Louvois J, Workman M R. Antibiotics for Salmonella meningitis in children. J Antimicrob Chemother 2000; 46(5):653-655.
Swann O, Everett D B, Furyk J S, Harrison E M, Msukwa M T, Heyderman R S.. Bacterial meningitis in Malawian infants <2 months of age: etiology and susceptibility to World Health Organization first-line antibiotics. Pediatr. Infect. Dis. J. 2014; 33(6):560-5.
Schutze G E, Schutze S E and Kirby R S. Extra intestinal Salmonellosis in children’s hospital. J Pediatr Infect Dis 1997; 16(5): 482-485.
Sighal V, Salem E K, Rajesh S M, Countinho A. Neonatal Salmonella typhi meningitis: A rare entity. J Clin &Diag Res 2012; 6(8):1433-1434
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