Genetic polymorphism of 17Y-STR loci in central of Iraq Population

Authors

  • Ban Ameen Forensic DNA Center Research and Training Al-Nahrain University, Baghdad, IRAQ.
  • Mohammed Mahdi Al-Zubaidi Forensic DNA Center Research and Training Al-Nahrain University, Baghdad, IRAQ.
  • Majeed Arsheed Sabbah Forensic DNA Center Research and Training Al-Nahrain University, Baghdad, IRAQ.
  • Mohammed I. Nader Institute of Genetic Engineering and Biotechnology for Postgraduate Studies, Baghdad University, Baghdad, IRAQ
  • Dhuha Salim Namaa Forensic DNA Center Research and Training Al-Nahrain University, Baghdad, IRAQ.
  • Hala K. Ibrahem Forensic DNA Center Research and Training Al-Nahrain University, Baghdad, IRAQ.
  • Thooalnoon Younes Al-Janabi Forensic DNA Center Research and Training Al-Nahrain University, Baghdad, IRAQ.
  • Asia Abdul Lateef Mahdi Forensic DNA Center Research and Training Al-Nahrain University, Baghdad, IRAQ.
  • Reem Husam Al-Tabra Forensic DNA Center Research and Training Al-Nahrain University, Baghdad, IRAQ.
  • Miriam Jasim Shehab Forensic DNA Center Research and Training Al-Nahrain University, Baghdad, IRAQ.
  • Nadhum Hussen Safir Forensic DNA Center Research and Training Al-Nahrain University, Baghdad, IRAQ.
  • Haider K. AL-Rubai Forensic DNA Center Research and Training Al-Nahrain University, Baghdad, IRAQ.
  • May Ridha Jaafar Forensic DNA Center Research and Training Al-Nahrain University, Baghdad, IRAQ.

Keywords:

Haplotype, Y chromosome, population structure, Arabian Peninsula

Abstract

In this study, a sample of 178 central of Iraq population  was analyzed using 17 Y- chromosome short tandem repeat (STR) polymorphisms. A total of 155 different haplotypes were identified, among which 135 were individual specific. The high haplotype diversity (0.994) supports the usefulness of Y-STR markers in central Iraq population diversity investigation. Our results suggest a close genetic relationship between Central of Iraq and other populations of the Arabian Peninsula, and an even more pronounced similarity of Kuwaiti populations and Yemenis and Saudi Arabians.

Downloads

Download data is not yet available.

References

Weidenreich, F. (1943). The skull of Sinanthropus pekinensis: a comparative study on a primitive hominid skull: Palaeontologia Sinica.

Cann, R. L.; Stoneking, M. and Wilson, A. C. (1987). Mitochondrial DNA and Human Evolution. Nature, 325(6099): 31-36.

Butler, J. M. (2006). Genetics and genomics of core short tandem repeat loci used in human identity testing. J. Forensic Sci. 51: 253–265.

Gill, P.; Brinkmann, B.; d’Aloja, E.; Andersen, J.; Bar, W. and Carracedo, A.et al. (1997 ). Considerations from the European DNA profiling group (EDNAP) concerning STR nomenclature. Forensic Sci. Int. 87: 185–192

Olaisen, B.; Bär,w.; Brinkmann ,B.; Budowle ,B.; Carracedo ,A.and Gill ,P.et al. (1998). DNA Recommendations 1997 of the International Society for Forensic Genetics. Vox Sang 74: 61–63 .

Budowle, B. (1998). CODIS and PCR-Based Short Tandem Repeat Loci: Law Enforcement Tools. in The Second European Symposium on Human Identification: 73–88.

Kayser, M .; Caglià, A.; Corach, D.; Fretwell , N.; Gehrig , C.;Graziosi , G. et al . (1997). Evaluation of Y-chromosomal STRs: a multicenter study. Int J Leg. Med 110: 125–133 .

Ahmadian, A.; Gharizadeh, B.; Gustafsson, A.C.; Sterky, F.; Nyren, P.; Uhlen, M. and Lundeberg, J. (2000). Single-nucleotide polymorphism analysis by pyrosequencing. Anal Biochem 280: 103-110.

Nordstrom, T.; Ronaghi, M.; Forsberg, L.; de Faire, U.; Morgenstern, R. and Nyren, P. (2000). Direct analysis of single-nucleotide polymorphism on double-stranded DNA by pyrosequencing. Biotechnol Appl Biochem 31 ( Pt 2): 107-112 .

Silva, N.M.; Pereira, L.; Poloni, E.S.a nd Currat, M. (2012). Human neutral genetic variation and forensic STR data. PLoS One. 7(11).

Peter, J. B.(2016). Recent advances in the study of fine-scale population structure in humans. Curr Opin Genet Dev. 41:98-105.

Maca-Meyer, N.; González, A.M.; Pestano, J.; Flores, C.; Larruga ,J.M.and Cabrera ,V.M. (2003). Mitochondrial DNA transit between West Asia and North Africa inferred from U6 phylogeography. BMC Genet. 4:1-11.

Kundu ,S. and Ghosh, S.K.(2015). Trend of different molecular markers in the last decades for studying human migrations. Gene. 556(2):81-90.

Hanson, E.K. and Ballantyne, J. (2007). An Ultra-High Discrimination Y Chromosome Short Tandem Repeat Multiplex DNA Typing System. PLoS ONE; 2 (8): e688.

Kuppareddi ,B. ; Suhasini, G.; Vijaya, M.; Kanthimathi, S.; Nicole ,M. and Martin ,T. (2010). Y Chromosome STR Allelic and Haplotype Diversity in Five Ethic Tamil Populations from Tamil Nadu, India, Leg. Med., 12: 265-269.

Kebareng ,J.T.(2015).Y-STR Profiling of Four South African Populations Using the University of the Western Cape 10 Locus Set .M.Sc. Thesis .Department of Biotechnology. University of the Western Cape .

Qamar ,R.; Ayub ,Q.; Mohyuddin, A.; Helgason, A.; Mazhar, K.; Mansoor ,A. et al.(2002). Y-Chromosome DNA variation in Pakistan. Am J Hum Genet. 70:1107-1124.

Underhill ,P.A. and Kivisild ,T.(2007). Use of y chromosome and mitochondrial DNA population structure in tracing human migrations. Ann Rev Genet. 41:539-564.

Willuweit, S. and Roewer, L. (2013). Y Chromosome Haplotype Reference Database. Forensic Sci. Int. Genet. 15: 43–48.

Goodwin ,William .(2016). Forensic DNA Typing Protocols. School of Forensic and Applied Sciences, University of Central Lancashire, Preston, Lancashire, UK .

Robert ,L .Green.; Ines ,C.R.;Cherisse ,B.and Lori ,K .Hennessy .(2005) .Developmental Validation of the QuantifilerTM real-time PCR kit for the Quantification of Human Nucler DNA sample ,J FORENSIC SCI, Vol 50 (4):1-17 .

Maura ,B.; Rixun, F .;Cristin ,E.O .;Lisa, M .C.; Manohar, R.F. and Jaiprakash, G.S. (2009). developmental validation of the quantifiler Y human male quantification kit for simultaneous quantification of total human and human male DNA and detection of PCR inhibitors in Biological samples . J Forensic SCI .vol 54(2):305-319.

Butler, J. M. (2003). Recent developments in Y-short tandem repeat and Y-single nucleotide polymorphism analysis.Forensic SciRev. 15(2): 91-111.

Nei,M. (1987). Molecular Evolutionary Genetics, Columbia University Press, New York.

Gusmao, L.; Butler, J.; Carracedo, A.; Gill, P.; Kayser, M.; Mayr W.R.and Morling ,N. et al. (2006). DNA Commission of the International Society of Forensic Genetics. DNA Commission of the International Society of Forensic Genetics (ISFG): an update of the recommendations on the use of Y-STRs in forensic analysis. Forensic Science International. 157: 187–197.

Willuweit, S. and Roewer, L. (2007). Y chromosome haplotype reference database YHRD: Update. Forensic Science International: Genetics, 1: 83‐87.

Filiz, O.; Nazli, B.; Ahmet, A. and Ayse, S.(2013). Population Data for 17 Y-STRs in Samples from the Southeastern Anatolia Region of Turkey. Int J Hum Genet, 13(2): 105-111.

Jasem, B.T .(2013). The Genetic Structure of the Kuwaiti and Failaka Island Populations: Y-chromosome & Mitochondrial DNA Variation.M.Sc.Thesis. Anthropology and the Graduate Faculty.University of Kansas.The USA.

AL-Zubaidi ,M. M and Majeed, A. Sabbah.(2017). Genetration of STR Profle from touched Glass Surface . Iraqi Journal of Botechnology, No. 2, 48‐54.

Imad, H. H.(2014). The Uses of Some DNA Markers in Forensic Analysis.Ph.D. department of Biology. College of Science. The University of Babylon. Iraq.

Share, F.M.(2014). Evaluation of Y-Chromosome Short Tandem Repeats(STR) Allele.Distribution in the Saudi population. M.Sc.Thesis. Department of Criminal Neighborhoods. College of Criminal Sciences. Naif Arab University for Security Sciences.KSA.

Serkan, D.; Cemal, G.; Mustafa, D.; Hasan, E. B.; Ramazan, T. and Damla, K. D.et al . (2017). A glimpse at the intricate mosaic of ethnicities from Mesopotamia: Paternal lineages of the Northern Iraqi Arabs, Kurds, Syriacs, Turkmens and Yazidis. PLOS ONE .12(11):1-21.

Tareq, Z. M. A.(2017). Study of Y-Chromosome STR Markers in United Arab Emirates Population. M.Sc. Thesis. Department of Biology. College of Science. United Arab Emirates University.UAE.

Al-Awadi ,S. J.; AL-Zubaidi, M. M.; Dhuha, , S .N.; Saleh ,T. Y.; shehab, M. j.; Hameed ,S. N.and Asia ,Abd- Alatief.( 2014). GENETIC VARIATION OF 15 AUTOSOMAL SHORT TANDEM REPEAT (STR) LOCI IN THE DIYALA- IRAQI POPULATION. International Journal of Biological & Pharmaceutical Research. 5(3): 131-135.

Haider, K. AL-Rubai.; AL-Zubaidi ,M. M.; Hala K. Ibrahem.;Ali, M.; Sahar, R.; Reem, H.; Sura ,N.; Asia, A. and Ali ,A.(2015). Revealed of A novel Allele in Wasit – Iraqi Population. Iraqi Journal of Science, , Vol 56, No.4A, pp: 2798-2806

Thooalnoon, Y. AL-Janabi.; AL-Zubaidi ,M. M.; Dhuha, S.Namaa.;Sura ,N.H.and Asia, Abd- Alatief. (2016).

Allele Frequency of 15 Autosomal Short Tandem Repeat (STR) Loci in Al Anbar - Iraqi Population. Iraqi Journal of Biotechnology, Vol. 15, No. 2 , 1-8

Saja ,D.K.; Muayad ,S. C.and AL-Zubaidi. M M.(2016). DNA-Profile Database Building Using STR DNA Marker For Diyala Province Population. International Journal of Advanced Research in Computer Engineering & Technology (IJARCET) Volume 5 Issue 3:615-619

Majeed, A. Sabbah1.; Halah, K. Ibrahim.; Al-zubaidi , M. M.; Hannan, K. Mahmood. ; Khalifa, M. S.; Qasim, S. Al-Mayah .and Ala ,H. B.(2017). Identification and quantification of Chimerism in bone marrow transplants leukemic patients. Iraqi Journal of Cancer and Medical Genetics (IJCMG). 10(1):41

Downloads

Published

2022-03-31

How to Cite

Ban Ameen, Mohammed Mahdi Al-Zubaidi, Majeed Arsheed Sabbah, Mohammed I. Nader, Dhuha Salim Namaa, Hala K. Ibrahem, Thooalnoon Younes Al-Janabi, Asia Abdul Lateef Mahdi, Reem Husam Al-Tabra, Miriam Jasim Shehab, Nadhum Hussen Safir, Haider K. AL-Rubai, & May Ridha Jaafar. (2022). Genetic polymorphism of 17Y-STR loci in central of Iraq Population. International Journal for Research in Applied Sciences and Biotechnology, 9(2), 347–356. Retrieved from https://ijrasb.com/index.php/ijrasb/article/view/413

Issue

Section

Articles

Similar Articles

You may also start an advanced similarity search for this article.

Most read articles by the same author(s)