Memory Enhancing Activity of Ginger (Zingiber officinale) , Its Treatments in Dementia and Alzheimers Disease
DOI:
https://doi.org/10.31033/ijrasb.9.3.14Keywords:
Zingiber officinale, Alzheimer’s disease, Degenerative disease, Dementia, NeuroprotectiveAbstract
As people live longer, they are becoming more susceptible to age-related ailments. Dementia patients throughout the world are crying out for better treatments, but the ones currently on the market do not meet those demands. Natural compounds, which have been used in traditional medicine due to their good effects and high tolerance, have recently grabbed the attention of the scientific community. Ginger (Zingiber officinale) has been shown to have anti-and anti-anti-vascular Alzheimer's dementia properties, two of the most common and devastating dementias. On Alzheimer's disease and vascular dementia models and in some human trials, ginger compounds were found to be therapeutic. These studies all point to a role for Ginger in both the treatment and prevention of this illness. Most people with Alzheimer's (AD) notice a decline in their cognitive abilities, although it is a neurological condition that affects the elderly in particular.Amyloid-beta buildup and tau hyperphosphorylation, as well as a lack of neurotransmitter balance, as well as cell death and inflammation, all contribute to the development of this disease. Finding new Alzheimer's disease medicines that can also alleviate side effects and pharmacokinetic difficulties is a desirable goal. Phytochemicals, which have been widely used by humans, can be used to fight a wide variety of ailments. Zingiber officinale, Gingeroids, Shogaoids, and Bornols were examined for memory problems. – Following the initial screening process, clinical trials are conducted in vitro. Intervening mechanisms like oxidative stress and apoptosis are among the most frequently addressed ones. A new study has linked Alzheimer's disease pathogenesis to signalling pathways. In vivo studies and clinical trials aid in the clarification of test findings and results scores in the area of cognitive functioning. Many conventional aspects of ginger intake in AD also appear in the current review. Ginger and its constituents' pharmacological and therapeutic properties will need to be studied in more depth in order to help treat and prevent memory problems.
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