Role of Crisper CAS9 Technology in the Diagnosis of Covid19

Abstract

Covid 19 is a pandemic disease came in existence in 2019. It is also called as the Human Corona Virus disease which is caused by SARS-CoV-2. Currently more than 215 countries around the world are being reported to be the sufferers of this disease. When this disease came into existence the diagnosis of the disease became a major task for the scientists and doctors across the world. A method known as RT PCR (Reverse Transcriptase Polymerase Chain Reaction) was applied during that crucial period to detect this disease. Among other diagnostic tools, CRISPER (Clustered Regularly Interspaced Short Palindromic Repeats) Cas system is being investigated for rapid and specific diagnosis of COVID-19. CRISPER-Cas technology is a highly flexible RNA guided endonuclease (RGEN) based nucleic acid editing tool that has transformed the field of genomics, gene editing, gene therapy and genome imaging. As compared to RT PCR which gives the result of diagnosis in 4-8 hours, the CRISPER Cas based method diagnose it within an hour. So, this technique came out to be a very appropriate and less time-consuming method for detection of the disease. This article is focuses on explaining the potential use of CRISPER Cas9 based approaches for the development of accurate and rapid diagnostic technique and antiviral therapy for detecting and limiting the spread of COVID-19. As this technique is new and advanced so can also be used for various other future applications too.